Pair Name	Withaferin A, Immune checkpoint blockers
Partner Name	Withaferin A
Disease Info	[ICD-11: 2C25.Z]	Lung cancer		Investigative
Biological Phenomena	Induction-->Immunomodulatory
Gene Regulation	Up-regulation	Expression	CD274	hsa29126
In Vivo Model	To establish the LLC syngeneic tumors, C57BL/6 mice were injected with a half million cells on the right flank and monitored until tumors were first palpable (2–3 mm diameter).
Result	Our results demonstrate that WFA sensitizes NSCLC to α-PD-L1 in part via activation of ROS.